With rules about pregnancy medications constantly changing, it can feel overwhelming to know what to do when you’re feeling sick.

It usually comes down to weighing the benefits for a mother with a health condition — even one as simple as a headache — against potential risks to her developing baby.

In the past, medications were assigned to five letter categories based on their level of risk Trusted Source. Category A was the safest category of drugs to take. Drugs in Category X were never to be used during pregnancy.

Below is a sampling of a few drugs that pregnant women should avoid.


Chloramphenicol is an antibiotic that’s usually given as an injection. This drug can cause serious blood disorders and gray baby syndrome.


Ciprofloxacin (Cipro) and levofloxacin are also types of antibiotics. These drugs could cause problems with the baby’s muscle and skeletal growth as well as joint pain and potential nerve damage in the mother.
Ciprofloxacin and levofloxacin are both fluoroquinolone antibiotics.


Fluoroquinolones can increase the risk of aortic tears or rupturesTrusted Source. This can result in life-threatening bleeding. People with a history of aneurysms or certain heart diseases may be at an increased risk of side effects.
Fluoroquinolones may also increase the chances of having a miscarriage, according to a 2017 study.


Primaquine is a drug that’s used to treat malaria. There isn’t a lot of data on humans who’ve taken this drug during pregnancy, but animal studies suggest it’s harmful to developing fetuses. It can damage blood cells in a fetus.


Sulfonamides are a group of antibiotic medications. They’re also known as sulfa drugs.

The majority of these types of drugs are used to kill germs and treat bacterial infections. They can cause jaundice in newborns. Sulfonamides may also increase the chances of having a miscarriage.


Trimethoprim (Primsol) is a type of antibiotic. When taken during pregnancy, this drug can cause neural tube defects. These defects affect brain development in a developing baby.


Codeine is a prescription drug used to relieve pain. In some states, codeine can be purchased without a prescription as cough medicine. The drug has the potential to become habit-forming. It can lead to withdrawal symptoms in newborns.


High doses of this OTC pain reliever can cause many serious problems, including:
delayed onset of labor
premature closing of the fetal ductus arteriosus, an important artery
hemorrhaging for both mother and baby
necrotizing enterocolitis, or damage to the lining of the intestines
oligohydramnios, or low levels of amniotic fluid
fetal kernicterus, a type of brain damage
abnormal vitamin K levels
Most experts agree that ibuprofen is probably safe to use in small to moderate doses in early pregnancy.

It’s especially important to avoid ibuprofen during the third trimester of pregnancy, however. During this stage of pregnancy, ibuprofen is more likely to cause heart defects in a developing baby.


Warfarin (Coumadin) is a blood thinner that’s used to treat blood clots as well as prevent them. It can cause birth defects.

It should be avoided during pregnancy unless the risk of a blood clot is more dangerous than the risk of harm to the baby.


Clonazepam (Klonopin) is used to prevent seizures and panic disorders. It’s sometimes prescribed to treat anxiety attacks or panic attacks.

Taking clonazepam during pregnancy can lead to withdrawal symptoms in newborns.


Lorazepam (Ativan) is a common medication used for anxiety or other mental health disorders. It can cause birth defects or life-threatening withdrawal symptoms in a baby after birth.

Finally, If you’re not sure whether or not a medication is safe to take during pregnancy, ask your doctor. Also, ask about updated studies, as pregnancy drug labels can change with new research.

Doctors, midwives, and Nurses please come and drop your advice and comments it’s very important to us.

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